Author: Habeeb F, Stables G, Bradbury F, et al.
anti-microbial effects of the inner gel from Aloe barbadensis Miller (syn. Aloe vera (L.) Burma. f. or Aloe vera), Infection is usually restricted to the top layer of colonic mucosa, where it causes ulceration and severe tissue damage, e pharmacology of natural products, blood leukocytes to show that both pro-inflammat.READ MORE

Authors Pegah Nasiri, Ali Malekzadeh Shafaroudi , Mahmood Moosazadeh, Delaram Poorkazemi, Javad Mehrani Sabet
Tooth brushing is a primary method to prevent the onset of oral diseases. Aloe vera is commonly used in dentistry as an herbal alternative due to its anti-inflammatory and anti-microbial actions; recently, it has been used in toothpaste formulations as an active agent, Aloe vera toothpaste can be used as an adjunct age.READ MORE

Authors Jannes van der Merwe, Jan Steenekamp, Dewald Steyn and Josias Hamman
solubility; bioavailability; excipients; dissolution, active pharmaceutical ingredients (APIs), poor solubility and low dissolution rates, luminal fluids of the gastrointestinal tract, excipients can be incorporated in the formulation to assist in the dissolution process of the drug, selected excipients (e.g., alkali.READ MORE

Author: Thu Han Le , Phan Se Yong, Park Hyun , Jin Jung, Seung Hyun Oh
tight junction-modulating effects of processed Aloe vera gel (PAG), comprising 5–400-kD polysaccharides as the main components, oral treatment of 143 mg/kg Polysaccharides Aloe Gel daily for 10 days improves the age-related leaky gut condition in old mice, by reducing their individual urinal lactulose/mannitol (L/M) .READ MORE

Author Lizelle T. Fox, Minja Gerber, Josias H. Hamman
transdermal route of administration offers an alternative pathway for systemic drug delivery with numerous advantages over conventional routes. Regrettably, the stratum corneum forms a formidable barrier that hinders the percutaneous penetration of most drugs, offering an important protection mechanism to the organism .READ MORE

Author: Sam Maher, Luca Casettari ,and Lisbeth Illum
Drug delivery systems that safely and consistently improve transport of poorly absorbed compounds across epithelial barriers are highly sought within the drug delivery field. The use of chemical permeation enhancers is one of the simplest and widely tested approaches to improve transmucosal permeability via oral, nasal.READ MORE

Author: Arshad H. Rahmani,1 Yousef H. Aldebasi,2 Sauda Srikar,1 Amjad A. Khan,3 and Salah M. Aly1,4
Treatment based on natural products, pivotal role in the treatment of diseases via modulation of biochemical and molecular pathways, aloe vera plays a therapeutic role in health management, Aloe vera in health maintenance based on its modulation of various biological activities, Pharmalogical effects of Aloe vera and i.READ MORE

Author: Moncrieff G, Cork M, Lawton S, Kokiet S, Daly C, Clark C.
pathophysiology of dry-skin conditions, emollient therapy, Dry skin (xerosis) is a common symptom of a number of skin conditions, including atopic dermatitis/eczema (AD/AE), ichthyosis, irritant contact dermatitis, psoriasis and asteatotic eczema, frequent washing, use of harsh detergents and exposure to low-humidity (.READ MORE

Author Tanya M. Barnes, Dalibor Mijaljica, Joshua P. Townley, Fabrizio Spada and Ian P. Harrison
Many dermatological conditions, such as eczema and psoriasis, are treated with topical therapeutic products. Instead of applying the active drug directly onto the skin, it is combined with a vehicle to aid in its delivery across the stratum corneum (SC) and into deeper regions of the skin, namely the epidermis and derm.READ MORE

Author: Endang Diyah Ikasari*, Anang Budi Utomo, Hanny Setyowati, Salasa Ayu Trisnawati
Ranitidine hydrochloride is a competitive inhibitor of histamine H2receptors, drug of choice in the treatment of ulcer, The drug has a short biological half-life of approximately 2–3 hours, thus a sustained release dosage form of ranitidine HCl is desirable. The aim of this study was to formulate and in vitro evaluat.READ MORE

Author: Van Smeden J, Janssens M, Gooris GS, et al.
skin protects the body from unwanted influences from the environment as well as excessive water loss, barrier function of the skin is located in the stratum corneum (SC),SC consists of corneocytes embedded in a lipid matrix. This lipid matrix is crucial for the lipid skin barrier function, relation between lipid modula.READ MORE

Author Prajakta N. Dongare, Anuja S. Motule, Mahesh R. Dubey, Manisha P. More, Prerna A. Patinge , Ravindra L. Bakal and Jagdish V. Manwar
Ethno-botanical information of such plants and their usage by indigenous cultures is useful in the conservation of traditional system of medicine, biodiversity, to promote health care system, therapeutic effects, Novel drug delivery systems for delivery of herbal drugs possesses several advantages over conventional for.READ MORE

Author K. Subramanian , S.Narmadha, U.Vishnupriya & V.Vijayakumar
Increasing research interest has been focused on controlled drug delivery through tablet form using synthetic and natural biocompatible polymers as carriers, synthetic polymer drug carriers will be safely metabolized, they will not impart any health benefit unlike the natural carriers such as chitosan, s.READ MORE

Author: Saidin, N.M., Anuar, N.K., Meor Mohd Affandi, M.M.R.
polysaccharides used in transdermal drug delivery system, system provides continuous controlled delivery of active ingredients through human skin and into the blood stream, Poor penetration of most drugs into the skin, increase the permeability of such drugs, natural polysaccharides in transdermal formulations has incr.READ MORE

Author: Jun Wu ,Ying Zhang,Zhongming Lv,Ping Yu,Weiqing Shi
Aloe vera has been widely used in health and nutritional supplements, Aloe vera soft capsule (ASC), safety evaluation of Aloe vera products before marketing, aloe vera not produce any marked subacute toxic effects, ASC showed no mutagenic activity in the Ames test and no evidence of potential to induce bone marrow micr.READ MORE

Authors Jun Wu ,Ying Zhang,Zhongming Lv,Ping Yu,Weiqing Shi
Aloe vera has been widely used in health and nutritional supplements, Aloe vera soft capsule (ASC), safety evaluation of Aloe vera products before marketing, aloe vera not produce any marked subacute toxic effects, ASC showed no mutagenic activity in the Ames test and no evidence of potential to induce bone marrow micr.READ MORE

Author K Sharma
hypertension is a chronic disease, which requires long-term treatment with drug therapy at steady state drug blood concentration. Candesartan cilexetil (CC) is a prodrug that is rapidly converted to candesartan (its active metabolite) during absorption from the gastrointestinal tract and confers blood pressure lowering.READ MORE

Author M. E. Morales, V. Gallardo, B. Clares, M. B. Garcia, and M. A. Ruiz
Cellulite, a clinical syndrome mainly affecting women, involves specific changes in conjunctive dermic and subcutaneous tissue, leading to vascular and hypertrophic alterations in adipose tissues and the consequent alteration of tissue structure, design of hydrogels and pluronic-lecithin organogels elaborated as vehicl.READ MORE

Author Rinda Gita Atikasari, Diah Adriani Malik, Retno Indar Widayati, Puguh Riyanto, Asih Budiastuti, Muslimin and Hardian
For toddlers younger than 36 months, most of them still use diapers, so diaper rashes frequently appear in the diaper area. To improve the skin barrier, a moisturizer is needed to repair the skin barrier, made with aloe vera as moisturizer for diaper dermatitis, topical ingredients with natural ingredients can be used,.READ MORE

Author: Balaji Srinivasan, Aditya Reddy Kolli, Mandy Brigitte Esch, James J. Hickman
Transepithelial/transendothelial electrical resistance (TEER) is a widely accepted quantitative technique to measure the integrity of tight junction dynamics in cell culture models of endothelial and epithelial monolayers. TEER values are strong indicators of the integrity of the cellular barriers before they are evalu.READ MORE

Author Pereira GG, Guterres SS, Balducci AG, Colombo P, Sonvico F
Burns are serious traumas related to skin damage, causing extreme pain and possibly death, Natural drugs such as Aloe vera and vitamin E have been demonstrated to be beneficial in formulations for wound healing. The aim of this work is to develop and evaluate polymeric films containing Aloe vera and vitamin E to treat .READ MORE

Authors Carien E. Beneke, Alvaro M. Viljoen and Josias H. Hamman
Drug dosage forms contain many components in addition to the active pharmaceutical ingredient(s) to assist in the manufacturing process as well as to optimize drug delivery, Due to advances in drug delivery technology, excipients are currently included in novel dosage forms to fulfil specific functions and in some case.READ MORE

Author: L. Bravo C
antioxidants, free radicals, flavonoids cardiovascular diseases, metabolism, diet, food, metals, molecular mass, nutritive value, plants, tannins , science of chemistry ,cancer prevention, metabolites, polyphenols, molecule, plant metabolites, phenolic molecules to highly polymerized compounds with molecular weights of.READ MORE

Author: Coviello, T.; Matricardi, P.; Marianecci, C.; Alhaique, F.
Hydrogels are three-dimensional, hydrophilic, polymeric networks, with chemical or physical cross-links, capable of imbibing large amounts of water or biological fluids. Among the numerous macromolecules that can be used for hydrogel formation, polysaccharides are extremely advantageous compared to synthetic polymers b.READ MORE

Author ImS‑A,OhS-T,SongS,KimM-R,KimD-S,WooS‑S,JoTH,ParkYI, LeeC-K.
Polysaccharides isolated from the gel of Aloe, Immunomodulatory activities, polysaccharides between 400 and 5 KDa exhibit the most potent macrophage-activating activity as determined by increased cytokine production, nitric oxide release, expression of surface molecules, and phagocytic activity.READ MORE

Author: Sinha, V.R.; Kumria, R.
Polysaccharides are bacterial enzymes have been used extensively in targeting of the drugs. Various polysaccharides have been investigated for colon specific drug delivery, natural polymers exhibit potential for drug delivery as they are comprised of polymers with a wide range of molecular weights resembles in the indi.READ MORE

Author Lee A, Chui PT, Aun CST,Gin T, Lau ASC.
patient with massive intraoperative bleeding after oral consumption of Aloe vera tablets, Aloe vera is a common herb used for antiinflammatory and antiarthritic activity, as well as antibacterial, hypoglycemic, and lipid-lowering effects. Compounds contained within Aloe vera can cause a reduction in prostaglandin synth.READ MORE

Author: Mária A.Deli
epithelial and endothelial barriers of the human body are major obstacles for drug delivery to the systemic circulation and to organs with unique environment and homeostasis, like the central nervous system. Several transport routes exist in these barriers, which potentially can be exploited for enhancing drug permeabi.READ MORE

Author: Panneerselvam Jithendra†, Abraham Merlin Rajam†, Thambiran Kalaivani, Asit Baran Mandal, and Chellan Rose*
aloe vera (AV), Collagen–Chitosan (COL-CS) scaffolds, composite preparations, complex composite, swelling property, hydrated condition, aloe vera concentration, enhanced growth and proliferation of fibroblasts, tissue engineering applications, scaffold or biomaterials that support cellular growth, differentiation, an.READ MORE

Author Prasanthi, V. Padmaja, Supriya Chatla
The use of natural products in the prevention and treatment has increased recently, prepare and evaluate the wound healing effect of Terramycin, to screen the wound healing effect of the formulated gel on the animals containing Aloe vera hydro gel and evaluate physical and microbial parameters for the formulated gel,.READ MORE

Author Pooja Jain, Mohamad Taleuzzaman, Chandra Kala, Dipak Kumar Gupta
develop the phytosomal gel of aloe vera extract for improved topical delivery. Aloe vera extract loaded phytosomal system was developed by fixing the amount of aloe vera extract and ethanol and by varying the concentration of lecithin, developed formulations were evaluated for vesicular size, entrapment efficiency, PDI.READ MORE

Author: Na, K.; Lkhagva-Yondon, E.; Kim, M.; Lim, Y.R.; Shin, E.; Lee, C.K.; Jeon, M.S.
Atopic dermatitis (AD) is a chronic inflammatory skin disease, dry itchy skin that results from defects in the epidermal barrier function. Aloe vera is used widely to promote general health and is administered topically to treat skin conditions such as eczema, burns and wounds, oral administration of processed A vera g.READ MORE

Author Hendrik JR Lemmer & Josias H Hamman , PhD
Inclusion of absorption-enhancing agents in dosage forms is one approach to improve the bioavailability of active pharmaceutical ingredients with low membrane permeability. Tight junctions are dynamic protein structures that form a regulated barrier for movement of molecules through the intercellular spaces across the .READ MORE

Author: Roman V. Moiseev, Peter W. J. Morrison, Fraser Steele, and Vitaliy V. Khutoryanskiy
development of advanced ocular formulations an important topic in pharmaceutical science, one of the ways to improve drug delivery to the eye is the use of penetration enhancers, these are defined as compounds capable of enhancing drug permeability across ocular membranes, overview of anatomical and physiological featu.READ MORE

Author: Harneet Marwah ,Tarun Garg, Amit K. Goyal &Goutam Rath
74% of drugs are taken orally and are not found to be as effective as desired, to improve such characteristics, transdermal drug delivery was brought to existence, this delivery system is capable of transporting the drug or macromolecules painlessly through skin into the blood circulation at fixed rate. Topical adminis.READ MORE

Author: Morné Fouché, Jan Steenekamp, Hannlie Hamman , Josias Hamman
many active pharmaceutical ingredients (APIs) exhibit poor solubility and low dissolution rates in aqueous environments such as the luminal fluids of the gastrointestinal tract, oral bioavailability of these compounds is usually very low as a result of their poor solubility properties, formulation strategies to improve.READ MORE

Authors Morné Fouché, Jan Steenekamp, Hannlie Hamman , Josias Hamman
many active pharmaceutical ingredients (APIs) exhibit poor solubility and low dissolution rates in aqueous environments such as the luminal fluids of the gastrointestinal tract, oral bioavailability of these compounds is usually very low as a result of their poor solubility properties, formulation strategies to improve.READ MORE

Author S. Maru, Sudarshan Singh, Shree H. N. Shukla
Mucilages are complex polymeric substances that are carbohydrates in nature and have garnered considerable interest in the food, pharmaceutical, and cosmetic industries for their functional, health, and nutritional benefits, polysaccharide macromolecules that form intricate molecular networks capable of retaining large.READ MORE

Author Patel , Chopra , Simran Chaurasia
As per Biopharmaceutical Classification System (BCS), one of the main concerns is low solubility and/or permeation of drugs resulting in reduced absorption and poor bioavailability, to overcome these issues, various strategies have been adopted, including the use of permeation enhancers which are also known as bioenhan.READ MORE

Author: Marina González-Larena, G. García-Llatas, G. Clemente, R. Barberá, M. J. Lagarda
plant sterol (PS)-enriched beverages, milk based fruit juice (MFJPS), fruit juice (FJPS) and milk beverage (MPS), phytosterol oxidation products,.READ MORE

Author: Mohammad Sadegh Amiri, Vahideh Mohammadzadeh , Mohammad Ehsan Taghavizadeh Yazdi , Mahmood Barani , Abbas Rahdar , and George Z. Kyzas
Gums are carbohydrate biomolecules that have the potential to bind water and form gels regularly linked with proteins and minerals in their construction. Gums have several forms, such as mucilage gums, seed gums, exudate gums, etc. Plant gums are one of the most important gums because of their bioavailability, main fea.READ MORE

Author: Di Colo G, Zambito Y, Zaino C.
drug delivery ,absorption enhancer, permeation enhancer , polymeric biomaterials, polymer synthesis, chitosan, paracellular, transport transcellular, transport tight junction , transmucosal drug administration across nasal, buccal, and ocular mucosae is noninvasive, eliminates hepatic first‐pass metabolism and harsh .READ MORE

Author: Vilas Asaram Arsul, Swaroop R Lahoti
Proper design and formulation of a dosage form requires consideration of the physical, chemical and biologic characteristics of the drug substances and pharmaceutical ingredients to be used in fabricating the product, excipients facilitate the formulation design and perform a wide range of functions to obtain desi.READ MORE

Author Toliopoulos I, Simos Y, Verginadis I, et al.
scientific investigation taking place into the function and the mechanisms of action of natural killer (NK) cells (NKCs), plant extracts and vitamin supplements may play an immunoregulatory role by stimulating the functionality of the NKCs,.READ MORE

Author Toliopoulos I, Simos Y, Verginadis I, et al.
scientific investigation taking place into the function and the mechanisms of action of natural killer (NK) cells (NKCs), plant extracts and vitamin supplements may play an immunoregulatory role by stimulating the functionality of the NKCs,.READ MORE

Author: Kharat Amol* and Pawar Pratibha
Novel drug delivery system is the method by which a drug is delivered can have a significant effect on its efficacy. Some drugs have an optimum concentration range within which maximum benefit is derived, and concentrations above or below this range can be toxic or produce no therapeutic benefit at all. From this, new .READ MORE

Author: Sudhakar Y, Bandyopadhyay AK.
white mustard mucilage from whole seeds of Sinapis alba was evaluated for its physical properties and compared with the other mucoadhesive polymers such as hydroxy propyl methylcellulose 5Cps and Carbopol 934P. Further, methanol precipitable solids from whole leaves of Aloe Vera L were used as permeation enhancer, to a.READ MORE

Author Barry, B.W.
Skin enhancement, Iontophoresis, Ultrasound, Liposomes, Optimization of drug delivery through human skin is important in modern therapy. This review considers drug–vehicle interactions (drug or prodrug selection, chemical potential control, ion pairs, coacervates and eutectic systems) and the role of vesicles and par.READ MORE

Author: Brayden D J, O’Mahony D J.
drug delivery technology, injection, infusion or by subcutaneous implants, Oral delivery, intestinal site of absorption and the physico-chemical properties of the agent, these labile compounds can be successfully formulated for oral delivery using intestinal-protective-targeting- and epithelial-permeating approaches, .READ MORE

Author Brayden D J, O’Mahony D J.
drug delivery technology, injection, infusion or by subcutaneous implants, Oral delivery, intestinal site of absorption and the physico-chemical properties of the agent, these labile compounds can be successfully formulated for oral delivery using intestinal-protective-targeting- and epithelial-permeating approaches, .READ MORE

Author: Gjylije Hoti,Adrián Matencio , Alberto Rubin Pedrazzo,Claudio Cecone,Silvia Lucia Appleton,Yousef Khazaei Monfared , Fabrizio Caldera andFrancesco Trotta
Nutraceuticals are bioactive or chemical compounds acclaimed for their valuable biological activities and health-promoting effects. The global community is faced with many health concerns such as cancers, cardiovascular and neurodegenerative diseases, diabetes, arthritis, osteoporosis, Delivery Systems for Nutraceutica.READ MORE

Author Mudhi AlAli , Maream Alqubaisy 1, Mariam Nasser Aljaafari , Asma Obaid AlAli , Laila Baqais , Aidin Molouki , Aisha Abushelaibi, Kok-Song Lai, Swee-Hua Erin Lim
Nutraceuticals are essential food constituents that provide nutritional benefits as well as medicinal effects, Nutraceuticals can be categorized into different classes based on their nature and mode of action, different classifications of nutraceuticals and their potential therapeutic activity, Nutraceuticals are known.READ MORE

Author Alonso M, Támbara Y, López M, Aguilar JC, Mayo O, Prieto E, Cremata, J, Gerwig, G, Kamerling, H, Hardy E. (2012)
polysaccharide is a long chain polymer made of acetylated mannose units, which are held together by β(1→4) linkages [1], inhibition of cellular proliferation with autonomous character (antitumoral and anticancerous action), antiviral action against a variety of viruses (e.g., herpes simplex, newcastle, measles, and .READ MORE

Author: Tewolde Mulu, Firomsa Teshale, Samuel Gemeda, Omprakash Sahu.
complex sugars, mucopolysaccharides, carbohydrates ,  therapeutic values, gastro-protective effect, structure and proper function and absorption of the digestive tract, capacity to stimulate the immune system , aloe vera  has special properties as a skin care product and as raw material for the manufacturing of hig.READ MORE

Authors Robert H. Davis
Aloe vera as a biological vehicle for the delivery of drugs, Aloe vera is used as a biological vehicle to deliver the estrogen, beta -estradiol and the androgen, testosterone propionate, provide treating symptoms and diseases mediated by hormonal deficiencies or amenable to treatment by hormones using Aloe vera as a bi.READ MORE

Author: Narsih, Sri Kumalaingsih, Susinggih Wijana , Jalan Aloe Vera High Molecular Polysaccharidesad Yani, Pontianak, Kalimantan Barat.
microencapsulation of natural antioxidant powder from Aloe vera (L.) skin was carried out using 10% maltodextrin, 0.3% tween 80 and drying at 600C; and the product was found to have free radical scavenging activity using DPPH (88.31%), total phenol (34.921%), and α tocopherol by HPLC (87.789mg/g), The FTIR analysis sh.READ MORE

Author Narsih, Sri Kumalaingsih, Susinggih Wijana , Jalan Aloe Vera High Molecular Polysaccharidesad Yani, Pontianak, Kalimantan Barat
microencapsulation of natural antioxidant powder from Aloe vera (L.) skin was carried out using 10% maltodextrin, 0.3% tween 80 and drying at 600C; and the product was found to have free radical scavenging activity using DPPH (88.31%), total phenol (34.921%), and α tocopherol by HPLC (87.789mg/g), The FTIR analysis sho.READ MORE

Author J. Vis. Ghaffarian, R.; Muro, S.
Sub-micrometer carriers (nanocarriers; NCs) enhance efficacy of drugs by improving solubility, stability, circulation time, targeting, and release. Additionally, traversing cellular barriers in the body is crucial for both oral delivery of therapeutic NCs into the circulation and transport from the blood into tissues, .READ MORE

Author: B Carien, V Alvaro, H Josias
Clinically, significant herb-drug interactions have been previously documented and can be pharmacodynamic and/or pharmacokinetic in nature. Pharmacokinetic interactions have been attributed to induction or inhibition of either metabolic enzymes or efflux transporters, study identified a modulation effect of efflux tran.READ MORE

Author: Marios Spanakis, Ioannis Vizirianakis, Ioannis Niopas
modulation of P-glycoprotein function by Aloe vera juice in Caco-2 cells, Aloe vera exhibited the capability to inhibit P-gp thus raising the possibility of the emergence of adverse drug reactions (ADRs), P-glycoprotein (P-gp), an ABC-transporter encoded by ABCB1 gene in humans localized in small intestine, is responsi.READ MORE

Author Agnieszka Kosinska, Wilfried Andlauer
Tight junction, Epithelial barrier modulation, Phenolic compounds, Paracellular transport, Food components, primary function of the human intestine is to absorb nutrients and water, important is its ability to act as a selective barrier to protect the human system. Intestinal epithelium is formed by a monolayer of epit.READ MORE

Author Agnieszka Kosinska, Wilfried Andlauer
Tight junction, Epithelial barrier modulation, Phenolic compounds, Paracellular transport, Food components, primary function of the human intestine is to absorb nutrients and water, important is its ability to act as a selective barrier to protect the human system. Intestinal epithelium is formed by a monolayer of epit.READ MORE

Author: Deepthi V. Tatiraju, Varsha B. Bagade, Priya J.Karambelkar, V. Jadhav, V. Kadam
Bioenhancers are chemical entities which promote and augment the bioavailability of the drugs which are mixed with them and do not exhibit synergistic effect with the drug, need for bioenhancers arises due to drugs which are poorly available, administered for long periods, toxic and expensive, Bioenhancers can be class.READ MORE

Author: Ojewole E, Mackraj I, Akhundov K, et al.
buccal mucosal route offers several advantages but the delivery of certain drugs can be limited by low membrane permeability, Aloe vera gel (AVgel) as a novel buccal permeation enhancer, Permeation studies were performed using Franz diffusion cells, and the drug was quantified by UV spectroscopy, buccal permeability pr.READ MORE

Author Vandana, K.R.; Yalavarthi, P.R.; Sundaresan, C.R.; Sriramaneni, R.N.; Vadlamudi, H.C.
Drug loading capacity, flux, in-vitro permeation, paws edema, percentage inhibition, stability, nimesulide emulsion for incorporation in Aloe vera gel base to formulate ‘nimesulide – Aloe vera transemulgel, anti-inflammatory studies, use of nimesulide is banned for oral administration, due to its potential for indu.READ MORE

Author: Makoto Takahashi, Dai Kitamoto, Yonathan Asikin, Kensaku Takara, Koji Wada
versatile skin care properties, enhance the bioavailability, interfacial and biochemical properties, liposomes, aloe vera induces proliferation and type I collagen synthesis in human fibroblasts, Type I collagen is a major structural protein and is found in large quantities in various parts of the body, especially in t.READ MORE

Author Junginger, H.E.; Verhoef, J.C.
low molecular weight transmucosal penetration enhancers for improved absorption of hydrophilic drugs (e.g. peptides and proteins), related mechanisms of action, novel types of macromolecular penetration enhancers, such as anionic polyacrylates and cationic chitosan and chitosan derivatives, have been developed. These p.READ MORE

Author: Junginger, H.E.; Verhoef, J.C.
penetration enhancers poly(acrylates) chitosan N-trimethyl chitosan mucosal membrane barriers transport mechanisms tight junctions hydrophilic drugs peptides proteins, low molecular weight transmucosal penetration enhancers for improved absorption of hydrophilic drugs, novel types of macromolecular penetration enhancer.READ MORE

Author Liu C, Leung MY, Koon JC, et al..
mannose-rich polysaccharide biological response modifier, stimulatory activity, potent stimulator of murine macrophage, tumoricidal properties of activated macrophage, Polysaccharides, Biological response modifier, Aloe vera, Macrophage, Aloe, chemistry, Animals, Antineoplastic Agents, pharmacology, Cell Line, Tumor, H.READ MORE

Author: Jambwa T, Viljoen A, Hamman JH.
Aloe gel , Aloe whole leaf , Controlled release , Powder flow , Matrix type tablet, Swelling , Mucoadhesiveness, Disadvantages of conventional immediate release tablets include fluctuations of drug plasma levels over successive administrations and forgotten doses may result in larger fluctuations that increase the chan.READ MORE

Author Jambwa T, Viljoen A, Hamman JH.
Aloe gel , Aloe whole leaf , Controlled release , Powder flow , Matrix type tablet, Swelling , Mucoadhesiveness, Disadvantages of conventional immediate release tablets include fluctuations of drug plasma levels over successive administrations and forgotten doses may result in larger fluctuations that increase the chan.READ MORE

Author J. Hochman, P. Artursson
therapeutic agents to exert their pharmacological effects, cross the biological membranes into the systemic circulation and reach the site of action, Drugs cross the membranes by one of two pathways; paracellular or transcellular, drugs are transported transcellularly, physiocochemical properties, The paracellular path.READ MORE

Author: J. Hochman, P. Artursson
therapeutic agents to exert their pharmacological effects, cross the biological membranes into the systemic circulation and reach the site of action, Drugs cross the membranes by one of two pathways; paracellular or transcellular, drugs are transported transcellularly, physiocochemical properties, The paracellular path.READ MORE

Author: Kathryn A Whitehead, Samir Mitragotri
needles are the primary mode of administering macromolecular drugs such as proteins and peptides, their limitations have motivated researchers to explore alternative routes. One of the most popular alternatives to parenteral drug administration is oral delivery, which requires transport across the intestinal epithelial.READ MORE

Author: Qiu Z, Jones K, Wylie M, Jia Q, Orndorff S.
activated macrophage cells and stimulated fibroblast growth, average molecular weight of 80,000 Dalton (Da), mannose, galactose, and glucose, fibroblasts, growth, neoplasms, hypersensitivity, ep,dermis, macrophages, polysaccharides Ultraviolet radiation, irradiation, mannose, immunosuppression.READ MORE

Author Zhang L, Tizard IR. Department of Veterinary Pathobiology, Texas A & M University College Station 77843, USA.
Acemannan, major carbohydrate fraction, aloe vera gel, acemannan could stimulate macrophage cytokine production, nitric oxide release, surface molecule expression, and cell morphologic changes, Macrophage activation RAW cells.READ MORE

Authors V Kusum Devi 1, Nimisha Jain, Kusum S Valli
Biocompatibility. A measure of how a biomaterial interacts in the body with the surrounding cells, tissues and other factors. A biomaterial is considered to have good biocompatibility if it does not generate a vigorous immune response, resists build-up of proteins and other substances on its surface that would hinder i.READ MORE

Author: Womble D, Helderman JH.
antiviral agent with immune enhancement capabilities, cytotoxic T-lymphocyte (Tc) function, lymphocyte cultures, chromium release, alloantigen, allostimulation, T-cells, immune enhancing.READ MORE

Author T Lebitsa, A
Aloe vera gel showed the ability to increase the bioavailability of vitamins and to enhance the in vitro transport of a macromolecular drug across intestinal epithelial cell monolayers, transepithelial electrical resistance and permeability of atenolol across excised intestinal tissue of the rat as well as the transpor.READ MORE

Author Beneke C., Viljoen A., Hamman J.
Aloe vera , Drug absorption enhancement , Transepithelial electrical resistance, In vitro transport, aloe materials on the transepithelial electrical resistance (TEER) as well as transport of a model compound (atenolol) in the apical-to-basolateral direction across rat intestinal tissue, Aloe vera gel polysaccharides .READ MORE

Author: L. Fox, M. Gerber, J. D. Preez, J. Plessis, J. Hamman
in vitro permeation enhancement effects of the aloe vera gel, ketoprofen as a marker compound, abdominal skin in Franz diffusion cells and the delivery of ketoprofen into the stratum corneum-epidermis and epidermis-dermis layers of the skin, tape stripping technique, Aloe vera gel material showed the highest potential .READ MORE

Author: Sun-A Im1, , Young-Ran Lee1, Young-Hee Lee1, Myung-Koo Lee1, Young In Park2, Sungwon Lee3, Kyungjae Kim3 and Chong-Kil Lee1
in vitro cell culture systems, immunomodulatory activity in vivo, route of administration was intraperitoneal or intramuscular, in vivo immunomodulatory, evidence for the immunomodulatory activity of orally administered Aloe vera gel, immunomodulatory polysaccharides, such as acetylated mannan, glucomannan, galactogala.READ MORE

Author: Sun‐A Im, Young-Ran Lee, Young‐Hee Lee, Myung-Koo Lee, Young In Park, Sungwon Lee, Kyungjae Kim, C. Lee
immunomodulatory component, Acemannan, a mixture of various length polymer chains of β-(1,4)-linked acetylated galactomannan isolated from aloe vera, may be the best-characterized immunomodulatory polysaccharides, immunoaugmenting activities of acemannan are mediated through the activation of macrophages, Acemannan al.READ MORE

Author Pereira, R. F., Carvalho, A., Gil, M. H., Mendes, A., & Bartolo, P. J.,
Hydrogel films composed of alginate and Aloe vera gel were developed for wound healing applications, Films with different formulations can be prepared for the different phases of the wound healing process, Aloe vera gel significantly improves the water absorption and the in vitro degradation properties of alginate hydr.READ MORE

Author: W Chen, Z Lu, A Viljoen, J Hamman Planta Medica, 2010
Aloe vera (L.) Burm. f. (Aloe barbadensis Miller) gel and whole leaf extract have effect on the permeability of Caco-2 cell monolayers, transepithelial electrical resistance, test solutions to measure reversibility of the effect, A. vera gel and whole leaf extract were able to significantly reduce the transepithelial e.READ MORE

Authors: Anja Haasbroek-Pheiffer, Clarissa Willers, Matthew Glyn, Lissinda du Plessis, Josias Hamman
co-administration of absorption enhancing agents with macromolecular drugs (e.g., protein and peptide drugs) has been identified as a means to improve the oral bioavailability of these drugs, Absorption-enhancing agents of natural origins, Aloe vera leaf (e.g., gel and whole leaf extract) have shown a potential to enh.READ MORE

Author Ram Kumar Sahua Jiyauddin Khanb
Poorly water-soluble drug, approximately 60–70% of the drug molecules are insufficiently soluble in aqueous media and/or have very low permeability to allow for their adequate and reproducible absorption from the gastrointestinal tract (GIT) following oral administration, Formulation scientists have to adopt various st.READ MORE

Author Talmadge J, Chavez J, Jacobs L, et al.
Aloe vera L. plant have demonstrated multiple clinical activities, hematopoietic activities of Aloe vera extracts , organ-specific in vitro
molecular profile , Preclinical studies have shown that such carbohydrate-containing extracts promote wound repair, augment reticuloendothelial function, modulate immune responses.READ MORE

Author: E.. Pretorius, C. Willers, J. Hamman, J. D. Steyn
oral administration route is still the most preferred by patients for drug treatment, but is unfortunately not suitable for all drug compounds, protein and peptide drugs (e.g. insulin) are usually administered by injection since they are unstable in the gastrointestinal luminal environment and have poor membrane permea.READ MORE

Author E.. Pretorius, C. Willers, J. Hamman, J. D. Steyn
oral administration route is still the most preferred by patients for drug treatment, but is unfortunately not suitable for all drug compounds, protein and peptide drugs (e.g. insulin) are usually administered by injection since they are unstable in the gastrointestinal luminal environment and have poor membrane permea.READ MORE

Author Marianne Ashford
The gastrointestinal tract is complex and many physiological factors affect absorption of drugs as they transit through the tract, physiological factors affecting absorption include the transit of dosage forms through the gastrointestinal tract, environmental factors, such as the pH, enzymes and food within the gastroi.READ MORE

Author Brown G.S.; Kelsey L.S.; Yates K.M.; Rosenberg L.J.; Talmadge J.E.
injectable acemannan, multiple therapeutic properties including activity in wound repair and as a biological agent for the treatment of neoplasia in animals as well as the ability to activate macrophages, hematoaugmenting properties, subcutaneous administration, increases splenic and peripheral blood cellularity, lymph.READ MORE

Author: A. Shirwaikar*, Annie Shirwaikar1, S. Lakshmana Prabu and G. Aravind Kumar
use of natural excipients to deliver the bioactive agents has been hampered by the synthetic materials. However, advantages offered by these natural excipients are their being non-toxic, less expensive and freely available. The performance of the excipients partly determines the quality of the medicines. The traditiona.READ MORE

Authors S. Selvadurai, S.Divya, A.Geetha, K.Rohini and S.Anbazhagan
use of natural excipients to deliver the bioactive agents, natural excipients are their being non-toxic, less expensive and freely available, performance of the excipients partly determines the quality of the medicines, substantial evolution from an inert and cheap vehicle to an essential constituent of the formulation.READ MORE

Author: Nikolai Petrovsky and Peter D Cooper
protective immune response, sufficient strength and duration to prevent or attenuate the virulence of pathogenic organisms, systemic delivery of immunologically active contaminants, immunogenicity, an adjuvant is defined as any compound that enhances the immune response, to enhance immunogenicity, provide antigen-dose .READ MORE

Author Saeedeh Darzi Kallyanashis Paul ,Shanilka Leitan ,Jerome A. Werkmeister and Shayanti Mukherjee
Aloe vera (AV), a succulent plant belonging to the Liliaceae family, has been widely used for biomedical and pharmaceutical application. Its popularity stems from several of its bioactive components that have anti-oxidant, anti-microbial, anti-inflammatory and even immunomodulatory effects. Given such unique multi-moda.READ MORE

Author Tai-Nin Chow J, Williamson DA, Yates KM, Goux WJ.
Acemannan, an acetylated β-1,4-linked glucomannan, Aloe vera gel carbohydrate, act as an immunostimulant, displaying adjuvant activity on specific antibody production [15] and enhancing the release of interleukin-1 (IL-1), interleukin-6 (IL-6), tumor necrosis fator-α (TNF-α) and interferon-γ (INF-γ) [22], Release .READ MORE

Authors: N Ranade, Arati; S. Ranpise, Nisharani; Ramesh, C.
Approach of novel drug delivery system (NDDS) overcomes the limitations of conventional dosage forms, delivery of herbal drugs , need to amalgamate the concept of NDDS in delivery of herbal constituents, deliver and retain two herbal constituents in stomach for better action against Helicobacter pylori induced gastric .READ MORE

Author: Chang Liu, Yan Cui, Fuwei Pi, Yuliang Cheng, Yahui Guo, and He Qian
Acemannan, considered one of the main bioactive polysaccharides of Aloe vera, immunoregulation, anti-cancer, anti-oxidation, wound healing and bone proliferation promotion, neuroprotection, and intestinal health promotion activities, biological activities of acemannan, structure-activity relationships of acemannan and .READ MORE

Author Liu, C.; Cui, Y.; Pi, F.; Cheng, Y.; Guo, Y.; Qian, H.
acemannan, considered one of the main bioactive polysaccharides of Aloe vera, possesses immunoregulation, anti-cancer, anti-oxidation, wound healing and bone proliferation promotion, neuroprotection, and intestinal health promotion activities, the biological activities of acemannan from Aloe vera determined by in vivo,.READ MORE

Author: OJHA KHYATI, SHENOY VRANDA, GUPTA SAUMYA, SUSEEM S.R. 2*
develop a controlled release hydrogel and to evaluate the efficiency of its drug delivery, synthetic polymer drug carriers will be safely metabolized, they will not impart any health benefit unlike the natural carriers such as starch and Aloe vera, release characteristics of ascorbic acid based hydrogel formulated usin.READ MORE

Author: Mahendran Sekar, Afikaah Sha An Ali, Ganesh Sundaram Subramanian, Vengata Subramani Manoharan , Isaac Jason J , Phan Ai Yean
Ultrasound is widely used in rehabilitation, primarily for improving connective tissue extensibility and pain relief in musculoskeletal injuries, and for promoting tissue healing and remodeling. Physiotherapists use therapeutic ultrasound more than any other electrophysiological modality, Topical analgesics will a.READ MORE

Authors Divya Bansal/ Bhargava , Manoj Choudhary, Nazneen Dubey, Aditya Ganeshpurkar, Vikas Pandey, Tushar Salukhe
Natural gums and mucilage which hydrates and swells on contact with aqueous media are used as additives in the formulation of hydrophilic drug delivery system, develop a new monolithic matrix system for complete delivery, zero-order manner over an extended time period using processed Aloe vera gel mucilage (PAG) as a r.READ MORE

Author: Crowley PJ, Martini LG.
molecular biology, physiological and disease processes, improving the performance of a medication, kinetics and dynamics of drug action, dose–response relationships, improve efficacy or reduce side effects, properties of any drug, composite of the innate activity and properties of the compound as modulated by the for.READ MORE

Author Crowley PJ, Martini LG.
molecular biology, physiological and disease processes, improving the performance of a medication, kinetics and dynamics of drug action, dose–response relationships, improve efficacy or reduce side effects, properties of any drug, composite of the innate activity and properties of the compound as modulated by the formu.READ MORE

Author Thanushree HR, Kumar GBK, Acharya A.
Diclofenac sodium has many side effects like nausea, vomiting, GIT disorders. These side effects can be reduced by converting into emulgel formulations. The emulgel formulation of Diclofenac Sodium was prepared by incorporation method, using span 20 and tween 20 as nonionic surfactants, clove oil and cinnamon oil as pe.READ MORE

Author: Tarkase K. N. and Danve V., Padmashree Dr. Vitthalrao Vikhe
achieve successful delivery of drug locally as well as systematically, rectal route, research, formulate and evaluate herbal extract Aloe Vera suppositories, Suppositories are inserted directly into the rectum to distribute their herbal powder to internal areas. Aloe Vera contains aloin, which is an anthraquinones glyc.READ MORE

Author Sasan Khadem nematollahi1 , Abbas Pardakhty2, Kobra Habibi3 , Mitra Mehrabani3
effectively deliver these biologicals, Niosomes are vesicles composed of non-ionic surfactants, which are biodegradable, relatively nontoxic, more stable and inexpensive, an alternative to liposomes, application in medicine, preparation of niosome, types of niosomes, characterisation and their applications, Bilayer, dr.READ MORE

Author: Ram Kumar Sahua Jiyauddin Khanb
Poorly water-soluble drug, approximately 60–70% of the drug molecules are insufficiently soluble in aqueous media and/or have very low permeability to allow for their adequate and reproducible absorption from the gastrointestinal tract (GIT) following oral administration, Formulation scientists have to adopt various st.READ MORE

Author: Panahi Y, Khedmat H, Valizadegan G, Mohtashami R, Sahebkar A.
use of Aloe vera (A. vera) for the treatment of gastroesophageal reflux disease (GERD) symptoms and compare its effects with those of omeprazole and ranitidine, Aloe vera is safe and well tolerated and reduced the frequencies of all the assessed GERD symptoms, with no adverse events requiring withdrawal, Gastroesophage.READ MORE

Author Hongyu Zhong, Xiang Li, Wanqi Zhang, Xiaoxiao Shen, Yuangang Lu and Hongli Li
Acne is a chronic disorder that affects almost 80% of adolescents and young adults, causing psychological and emotional distress, Acne is a chronic disorder of pilosebaceous units, which is characterized by comedones, inflammatory papules, pustules, cysts, and nodules, affecting almost 80% of adolescents and young adul.READ MORE

Author Alam S, Ali I, Giri KY, Gokkulakrishnan S, Natu SS, Faisal M, Agarwal A, Sharma H.
pharmacological agents include corticosteroids, enzymes, interferon-gamma, antioxidants, methylxanthine derivatives, placental extracts, immune milk, turmeric, colchicine, tea pigments, aloe vera, and spirulina, Antioxidants are believed to improve the symptoms by protecting cells from damage from free radicals. Agents.READ MORE

Authors Delly Ramadon, Maeliosa T. C. McCrudden, Aaron J. Courtenay & Ryan F. Donnelly
Transdermal drug delivery systems , research topic in pharmaceutical technology area, developed pharmaceutical products in global market, delivery routes, such as oral and parenteral, applications of transdermal technologies, transdermal drug delivery systems and enhancement strategies, development of first-generation .READ MORE

Author: Delly Ramadon, Maeliosa T. C. McCrudden, Aaron J. Courtenay & Ryan F. Donnelly
Transdermal drug delivery systems , research topic in pharmaceutical technology area, developed pharmaceutical products in global market, delivery routes, such as oral and parenteral, applications of transdermal technologies, transdermal drug delivery systems and enhancement strategies, development of first-generation .READ MORE

Author: Ward, P.D.; Tippin, T.K.; Thakker, D.R.
intestinal epithelium is a major barrier to the absorption of hydrophilic drugs. The presence of intercellular junctional complexes, particularly the tight junctions (zona occludens), renders the epithelium impervious to hydrophilic drugs, which cannot diffuse across the cells through the lipid bilayer of the cell memb.READ MORE

Author: Chen, W.
Aloe vera (L.) Burm. f. – Asphodelaceae – gel – whole leaf extract – absorption enhancement – Caco‐2, confocal laser scanning microscopy, F-actin, FITC-dextran, tight junctions, transepithelial electrical resistance, co-administration of absorption enhancers,.READ MORE

Author: Ranade A, Ranpise NS, Ramesh C.
treatment for Helicobacter pylori‑induced peptic ulcer includes a 14‑day “triple therapy” of two antibiotics and a proton pump inhibitor. However, the current therapy has side‑effects like stomach upset, non‑compliance, incomplete absorption of drug and antibiotic resistance, best possible alternative is to.READ MORE

Author Jani GK, Shah DP, Jain VC.
Natural gums and mucilage have been widely explored as pharmaceutical excipients. The goal of this study was to extract mucilage from the leaves of Aloe barbadensis Miller and to study its functionality as an excipient in pharmaceutical sustained-release tablet formulations, Sustained-release dosage forms are prepared .READ MORE

Author Maharjan H. Radha and Nampoothiri P. Laxmipriya∗
Aloe vera, medicinal properties, Immunomodulatory effect, own regulates lipopolysaccharide-induced inflammatory cytokine production and expression of NLRP3 (NACHT, LRR, and PYD domain-containing protein 3) inflammasome
in human macrophages, inhibit the inflammatory process, reduction of leukocyte adhe-sion, as well .READ MORE

Author: Saeed Alqahtani, Loqman Mohamed, Amal Kaddoum
For orally administered drugs, their intestinal absorption and hepatic metabolism are key players for determining a drug’s systemic bioavailability and thus therapeutic effect. Drug absorption and metabolism are both complicated processes, with many physicochemical and physiological factors involved. Understanding the .READ MORE

Author: Bani Ahluwalia 1 2, Maria K Magnusson 1, Fredrik Larsson 2, Otto Savolainen 3 4, Alastair B Ross 3 5, Lena Öhman 1
immunomodulation, bioactive component(s), polysaccharides (acemannan), human blood T cell activity, T cell phenotype and proliferation, 1H-NMR spectroscopy, T cell activation, proliferation, apoptosis, and cell-death in vitro, metabolomics, metabolite profile, gas chromatography mass spectrometry (GC-MS) for metabolite.READ MORE

Author Endang Diyah Ikasari, Intan Martha Cahyani
several factors that influence dissolution test in vitro such as dissolution media. The AIF media (Atrial Intestinal Fluid) and the SIF media (Simulated Intestinal Fluid) media are among the media that can be used in the dissolution test. Mucoadhesive microgranule of ranitidine HCl using a combination polymer of aloe v.READ MORE

Author: W Chen, J Hamman, A Vlijoen – African Journal of Traditional,
Oral drug delivery is considered as the preferred route of administration, but the bioavailability of orally administered hydrophilic, macromolecular drugs is usually poor because of the hostile gastric environment and also poor gastrointestinal mucosal permeability. Co-administration of absorption enhancers is one way.READ MORE

Authors : Bianca Peterson, Morné Weyers , Jan H. Steenekamp, Johan D. Steyn, Chrisna Gouws and Josias H. Hamman *
bioenhancer; cytochrome P450; drug absorption enhancer; efflux; metabolism; P-glycoprotein; pharmacokinetic interaction; tight junction, new chemical entities are discovered with high therapeutic potential, compounds exhibit unfavorable pharmacokinetic properties due to poor solubility and/or poor membrane permeation c.READ MORE

Author E. Leucuta, Sorin
Activation-modulated DDS; Biodegradable Systems; Drug delivery systems; Enzyme Activated; Hopfenberg Model; Microreservoir Partition Controlled DDS; Osmotic Pressure Activated DDS; Polymer Matrix-diffusion DDS; medicine; modified release; pharmacy, new generations of pharmaceutical systems: medicines with extended rele.READ MORE

Author: E. Leucuta, Sorin
Activation-modulated DDS; Biodegradable Systems; Drug delivery systems; Enzyme Activated; Hopfenberg Model; Microreservoir Partition Controlled DDS; Osmotic Pressure Activated DDS; Polymer Matrix-diffusion DDS; medicine; modified release; pharmacy, new generations of pharmaceutical systems: medicines with extended rele.READ MORE

Author: Vinson J A, Al Kharrat H, Andreoli L.
effect of consumption of Aloe vera liquid preparations on the absorption of water- or fat-soluble vitamins, Aloe on the human absorption of vitamins C and E, vitamin supplements, plasma bioavailability of vitamins C and E, supplementation of vitamin C with Aloe Gel area was 304%,For vitamin E, the results for the relat.READ MORE

Authors FIRMANSYAH, Ferdy; VAJRIKA, Silvi Ayu; MUHTADI, Wildan Khairi
Aloe vera is efficacious as an antibacterial activity , treat acne caused by the bacteria Propionibacterium acnes, viscosity, dissolution, diffusion, and bioavailability of the preparation, determine the effect of the combination of Carbopol 940 base and HPMC as a gelling agent on the physical properties and antibacte.READ MORE

Author: Bland,
effect of oral Aloe vera juice supplementation on gastric pH, stool specific gravity, protein digestion/absorption, and stool microbiology. Results indicate that supplemental oral Aloe vera juice is well tolerated by most individuals and has favorable effects upon a number of gastrointestinal parameters, A discussion o.READ MORE

Author Garnick JJ, Singh B, Winkley G.
gel containing silicon dioxide, aloe vera, and allantoin in the healing of recurrent aphthous ulcers, parameters used to evaluate healing were number of lesions during a 3-to-4-month period, length of the interval between ulcers, size of ulcers, and pain from ulcers.READ MORE

Author Eshghi F, Hosseinimehr SJ, RAloe Vera High Molecular Polysaccharidesani N, Khademloo M, Norozi MS, Hojati O.
Aloe vera is an herbal medicine, which has wound healing effects in burn injury. This study assessed the effects of Aloe vera cream in reducing postoperative pain, post defection pain, and its promotion of wound healing after open hemorrhoidectomy, cream containing Aloe vera versus a placebo cream on posthemorrhoidecto.READ MORE

Author Tafara Jambwa, Alvaro Viljoen and Josias Hamman
develop novel drug delivery systems, Excipients from renewable sources, Aloe vera and Aloe ferox as excipients, physical characteristics, mucoadhesive properties, swelling behaviour and drug release kinetics, immediate-release tablet as dosage form is that drug plasma levels actuate over successive doses, Modification .READ MORE

Author: Haasbroek A1, Willers C2, Glyn M3, du Plessis L4, Hamman J5.
absorption enhancing agents, macromolecular drugs (e.g., protein and peptide drugs), oral bioavailability, Absorption-enhancing agents of natural origins, green chemistry, enhance drug permeation across the intestinal epithelial barrier, a clear decrease in transepithelial electrical resistance (TEER) of Caco-2 cell mo.READ MORE

Author: Himansu Bhusan Samal, Itishree Jogamaya Das, Ch. Niranjan Patra, P. N. Murthy
develop and evaluate dental film containing Aloe Vera extracts for the treatment of Periodontitis, Aloe Vera shows wide spectrum of antibacterial activity against several periodontal pathogen and hence selected for site specific delivery for the treatment of Periodontitis. Aloe vera is formulated into dental films by s.READ MORE

Author: Hindustan Abdul Ahad, Sreeramulu J, Hima Bindu V, Chitta Suresh Kumar, Kishore Kumar Reddy B, Chandana Rekha V , Sivaji S
develop matrix tablets of Glimepiride with Aloe barbadensis miller leaves mucilage and Povidone and to study its functionality as a matrix forming agent for sustained release tablet formulations, mucilage of Aloe barbadensis miller leaves clinically and experimentally proved anti-diabetic activityand release retardant .READ MORE

Author Abolfazl Aslani, Alireza Ghannadi, Razieh Raddanipour
design and evaluate the formulation of Aloe vera chewing gum with an appropriate taste and quality with the indications for healing oral wounds, such as lichen planus, mouth sores caused by cancer chemotherapy and mouth abscesses as well as reducing mouth dryness caused by chemotherapy, Aloe vera powder, the carbohydra.READ MORE

Author Abolfazl Aslani, Alireza Ghannadi, Razieh Raddanipour
design and evaluate the formulation of Aloe vera chewing gum with an appropriate taste and quality with the indications for healing oral wounds, such as lichen planus, mouth sores caused by cancer chemotherapy and mouth abscesses as well as reducing mouth dryness caused by chemotherapy, Aloe vera powder, the carbohydra.READ MORE

Author: Narayana Charyulu Rompicherla , Punam Joshi 1, Amitha Shetty, Kalvatala Sudhakar ,Hawraz Ibrahim M. Amin , Yachana Mishra, Vijay Mishra , Aqel Albutti * and Naif Alhumeed
Topical treatments are a potential therapeutic option for the therapy of osteoarthritis, with significant data supporting the effectiveness and safety of topical formulation. Topical gel formulations may offer an alternative to oral formulations to relieve osteoarthritis (OA) pain while decreasing systemic exposure. To.READ MORE

Author Narayana Charyulu Rompicherla , Punam Joshi 1, Amitha Shetty, Kalvatala Sudhakar ,Hawraz Ibrahim M. Amin , Yachana Mishra, Vijay Mishra , Aqel Albutti * and Naif Alhumeed
Topical treatments are a potential therapeutic option for the therapy of osteoarthritis, with significant data supporting the effectiveness and safety of topical formulation. Topical gel formulations may offer an alternative to oral formulations to relieve osteoarthritis (OA) pain while decreasing systemic exposure. To.READ MORE

Author: Ranade AN, Wankhede SS, Ranpise NS, Mundada MS.
Usual treatment for Helicobacter pylori-induced peptic ulcer includes a ‘triple therapy’ consisting of two antibiotics (amoxicillin and clarithromycin) and a proton pump inhibitor (omeprazole), retain the drug in stomach for better antiulcer activity and substituting one of the synthetic drugs in this therapy with .READ MORE

Author: Kulkarni, G.T.; Gowthamarajan, K.; Dhobe, R.R.; Yohanan, F.; Suresh, B.
polysaccharide hydrogel was isolated from the seeds of Tamarindus indica (tamarind) and was used as release modifier for the preparation of diclofenac sodium spheroids, using extrusion-spheronization technique, the process was studied for the effect of variables to arrive at spheroids with satisfactory particle shape, .READ MORE

Author Habibur Rahman*, Telny Thomas Chungath, Kuppusamy Selvakumaraswamy and Chandrasekar R.
pharmaceutical applications, harried contained in the
gel of the leaves. On the other hand, the important pharmaceutical applications such as the use of the dried Aloe vera gel powder as an excipient in sustained release (SR) pharmaceutical dosage, release matrix tablets, dissolution enhancer, Korsemayer Peppas model v.READ MORE

Author Rishabha Malviya, Pranati Srivastava and G.T. Kulkarni
With the increasing interest in polymers of natural origin, the pharmaceutical world has compliance to use most of them in their formulations. Moreover, the tremendous orientation of pharma world towards these naturally derived polymers has become a subject of increasing interest to discover, extract and purify such co.READ MORE

Author: W. Gerber, J. D. Steyn, A. F. Kotzé, J. Hamman
Simultaneous oral intake of herbs, supplements, foods and drugs with other drug(s) may result in pharmacokinetic or pharmacodynamic interactions with the latter, pharmacokinetic interactions include the improvement of the bioavailability of a drug (i.e., by enhancing absorption and/or inhibiting metabolism) or prolonga.READ MORE

Author: Antoni FG, Pablo S, Susana S, Carmen R.
bioactive polysacharide, cell wall polysaccharides, aloe parenchyma tissues, Pectic polysaccharides, bioactivity.READ MORE

Author DAVID DAHLGREN
Before an orally administered drug reaches the systemic circulation, it has to dissolve in the intestinal fluids, permeate across the intestinal epithelial cell barrier, and pass through the liver, the permeation rate of drug compounds can be low and show regional differences, regional intestinal permeability values of.READ MORE

Author Ruixuan Geng, Seong-Gook Kang, and Tao Tong
Skin photoaging is mainly induced by ultraviolet (UV) irradiation and its manifestations include dry skin, coarse wrinkle, irregular pigmentation, and loss of skin elasticity, Dietary supplementation of nutraceuticals with therapeutic and preventive effects against skin photoaging, cellular and molecular mechanisms of .READ MORE

Author: Carla Pereira, J. Costa, B. Sarmento, Francisca Araújo
oral administration of drugs is still a huge challenge because of the harsh conditions of the gastrointestinal tract, drug design and development, permeability behavior of those drugs are essential to improve the drug delivery field, Caco-2 model has been the gold-standard in vitro method used for such purposes.READ MORE

Author A. Pradeep, E. Agarwal, S. Naik
controlled clinical trial was designed to evaluate the clinical and microbiologic effects of a commercially available dentifrice containing aloe vera on the reduction of plaque and gingival inflammation in patients with gingivitis, Toothpaste containing aloe vera showed significant improvement in gingival and plaque in.READ MORE

Author Mansour G, Ouda S, Shaker A, Abdallah HM.
clinical efficacy, and safety of newly customized natural oral mucoadhesive gels, containing either aloe vera or myrrh as active ingredients, in the management of minor recurrent aphthous stomatitis (MiRAS), w natural gels, containing aloe vera and myrrh, were prepared in a concentration of (0.5% w/w), in addition to a.READ MORE

Author: Trizel du Toit, M. Malan, H. J. Lemmer, C. Gouws, M. Aucamp, Wilma J Breytenbach, J. Hamman
macromolecular drugs such as proteins are mainly administered by means of injections due to their low intestinal epithelial permeability and poor stability in the gastrointestinal tract, permeation enhancing effects and not tissue damage, Aloe Vera Gel gel increased paracellular permeation of a macromolecular compound .READ MORE

Author: Endang Diyah Ikasari*, Anang Budi Utomo, Hanny Setyowati
polymer for pharmaceutical industry, Aloe vera gel may be employed to effectively deliver poorly absorbable drugs through the oral route of drug administration. Ranitidine hydrochloride is a drug of choice in the treatment of ulcer. The drug has a short biological half-life of approximately 2-3 hours, thus a sustained .READ MORE

Author Mansourian A, Momen-Heravi F, Saheb Jamee M, Esfehani M, Khalilzadeh O, Momen Beitollahi J.
Corticosteroids are the mainstay for treatment of oral lichen planus (OLP), Triamcinolone acetonide, therapeutic effects of aloe vera (AV) mouthwash with triamcinolone acetonide 0.1% (TA) on OLP, Thongprasom index, AV mouthwash is an effective substitute for TA in the treatment of OLP..READ MORE

Authors Eli Harlev1,Eviatar Nevo1,Ephraim P.Lansky1,Rivka Ofir2,Anupam Bishaye e3
Aloeʼs pharmaceutical potential, against neoplastic disease, anticancer biological mechanism of acemannan, pluripotent effector cells, aloe induce macrophage activating activity, immunobiology, Aloe polysaccharide, combined with chemotherapeutic agents, such as cisplatin (DDP) and
5-fluorouracil (5-FU), enhances the t.READ MORE

Author: Tae Hyung JO, Seon Gil Do, Eun Ju Shin, Hye In Jang, Jin Wan Kim, Ghe Whan Ahn, Seung Won Yang, Jin Hee Im, Jeong Bum Nam, Soo Gyeom Kim , Ken Jones
aloe vera sprout concentrate or extract having cell growth promotion, antioxidant, and anti-allergy effects, and to a skin cell growth promoting, antioxidant, and anti-allergy pharmaceutical composition and functional health food or cosmetics containing the aloe vera sprout concentrate or extract as an active ingredien.READ MORE

Author: Yagi A, Hamano S, Tanaka T, Kaneo Y, Fujioka T, Mihashi K. Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Japan.
Aloemannan – Aloe vera – Asphodelaceae – fluoresceinyl isothiocyanate aloemannan – metabolism – degraded fluoresceinyl thiocyanate aloemannan – fast atom bombartment mass spectrometry – matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.READ MORE

Author: Boudreau M D, Beland F A.
Aloe barbadensis (Miller), a topical and oral therapeutic, Herbal remedies are used either as topical agents or as dietary supplements for both general health promotion and the specific treatment of ailment symptoms, consumption at various concentrations in liquid, powder, and tablet form, ingestion of Aloe vera, small.READ MORE

Author ULBRICHT CATHERINE ET AL
Alopecia (hair loss), Alzheimer’s disease, antioxidant, arthritis (osteoarthritis and rheumatoid arthritis), asthma, bacterial skin infections, candida skin infections, chronic fatigue syndrome, chronic leg ulcers, congestive heart failure, corneal abrasions/ulcers, coronary artery disease prevention, diabetic ulcers.READ MORE

Author: Chander Pal Singh Verma, Santosh Verma, Mahendra Singh Ashawat, Vinay Pandit
the ideal characteristic of bioenhancers includes inertness, nontoxic, cost effective and decrease the dose of active constituents. There are lots of natural bioenhancers available such as piperine quercetin, niaziridin, genistein, glycyrrhizin, curcumin, the review focus on plant based bioenhancers and their active p.READ MORE

Author: Rachana Sharma
Drug delivery, Controlled drug delivery, Nanotechnology, increasing interest in this area has been focused on controlled drug delivery using biocompatible polymers as carriers in recent years and aloe gel is an example of such category. Its ease of extraction and processing has made it possible to be used as nano drug .READ MORE

Author S.Arunkumar and M. Muthuselvam.
Aloe vera phyto chemical compounds and antimicrobial
Activity, Tannin, Saponin, Flavonoids and Terpenoids gave positive results and phlobactanins and Steriods and Steriods gave negative results. In the GC-MS analysis, bioactive phytechemical compounds, antimicrobial activity selected human clinical pathogens, Antifunga.READ MORE

Author: Eli Harlev , Eviatar Nevo , Ephraim P. Lansky , Rivka Ofir , Anupam Bishayee
Aloe vera; acemannan; applications; biological activity; polysaccharide; structure, immunoregulation, anti-cancer, anti-oxidation, wound healing and bone proliferation promotion, neuroprotection, and intestinal health promotion activities, structure-activity relationships of acemannan, medical applications, pharmacolog.READ MORE

Author: Zaira López,Gabriela Núñez-Jinez,Guadalupe Avalos-Navarro,Gildardo Rivera,Joel Salazar-Flores,José A. Ramírez,Benjamín A. Ayil-Gutiérrez,and Peter Knauth
supplements from Aloe vera, concentrated powders (starting products), final product at a concentration of 1x, meaning g/L for decolorized and spray-dried inner leaf powder (ILG), Aloe fillet, Aloe gel, thick watery inner parenchyma, secondary metabolites such as complex polyphenols (e.g., tannins and flavonoids), ligni.READ MORE

Author: C. Bender, S. Graziano, Benno F. Zimmerman, Helmut H. Weidlich
teas and herbal infusions, health promoters due to their content in antioxidant compounds, antioxidant capacities, through chemical and cellular assays, infusions and as ingredients in cosmetics products and in food formulations, protection against peroxyl radicals under physiological conditions, cell-based assay, cell.READ MORE

Author: Sam Maher, David J. Brayden, Luca Casettari, and Lisbeth Illum
application of permeation enhancers (PEs) to improve transport of poorly absorbed active pharmaceutical ingredients across the intestinal epithelium is a widely tested approach, permeation enhancers represent a key constituent of conventional oral formulations, permeation enhancer, oral delivery, formulation, permeabil.READ MORE

Author Woźniak A, Paduch R.
Ocular diseases are currently an important problem in modern societies. Patients suffer from various ophthalmologic ailments namely, conjunctivitis, dry eye, dacryocystitis or degenerative diseases. Therefore, there is a need to introduce new treatment methods, including medicinal plants usage. Aloe vera [Aloe barbaden.READ MORE

Author Tarameshloo M, Norouzian M, Zarein-Dolab S, Dadpay M, Mohsenifar J, Gazor R.
Wound healing, a complex interaction among cells, extracellular matrix, blood vessels, proteases, cytokines, and chemokines, is still a controversial topic in surgical medicine, several complications such as delayed wound healing, superficial wound infection and post-operative/post-traumatic neuropathic chronic cutaneo.READ MORE

Aisha Saleem, Irum Naureen, Muhammad Naeem, Hafiza Safoora Murad, Samra Maqsood, Gulnaz Tasleem
Digestive Diseases Protection, Aloe vera extract (50%) increased cell viability of dental pulp stem cells being useful for avulsed broken teeth. This effect is attributed to polysaccharides, mainly acemannan, by inducing osteogenic-specific gene expressions, DNA synthesis, growth factor, and JAK-STAT pathway. Moreover,.READ MORE

Author Oliver Grundmann , BPharm,ms,PHD
properties of Aloe vera, promote the health of society, Clinical trial, improve skin integrity, retain skin moisture and integrity, Magnesium lactate available in the gel can prevent the production of histamine that causes itching and irritation of the skin, enhances the immune system and the synthesis of cytokines. Al.READ MORE

Author A Yagi
aloe high molecular fractions (ALOE VERA HIGH MOLECULAR POLYSACCHARIDES) were obtained in original and natural form containing less than 10 ppm of barbaloin. ALOE VERA HIGH MOLECULAR POLYSACCHARIDES mainly contained high molecular fractions, such as polysaccharide (acemannan) and glycoprotein (verectin) showing immunom.READ MORE

Author: G Ital Dermatol Venereol. 2009;144(1):85–91 Feily A, Namazi MR..
Aloe vera or Aloe barbadensis, dermatology-oriented, Topical application of aloe vera, effective for genital herpes, psoriasis, human papilloma virus, seborrheic dermatitis, aphthous stomatitis, xerosis, lichen planus, frostbite, burn, wound healing and inflammation, biological vehicle and an anti-microbial and antifun.READ MORE

Authors: Anirban Ray, Sampad Ghosh
nutraceutical and cosmeceutical potential of Aloe vera L., human well-being, Polysaccharides are demonstrated as the major component compounds for the bioactivities of Aloe Vera Gel gel, bioactivities, composition, and proportion of gel-components significantly influence the bioactive potential of aloe gel, aloe gel wo.READ MORE

Author: Joana Simõesa, Fernando M. Nunesb, Pedro Dominguesa, Manuel A. Coimbraa, M. Rosário Dominguesa.
Aloe vera acemannan, backbone of β-(1→4)-linked D-mannose, mannans, acetyl groups, high abundance of acetylated residues, lower branching, shorter chains, and higher acetylation seems to promote the immunostimulatory activity attributed to these polysaccharides..READ MORE

Author: Jitendra Sainy1, Umesh Atneriya, Jagjiwan lal kori, Rahul Maheshwari
Desoximetasone, Plaque psoriasis; Emulgel; Skin penetration; Skin diseases; Kinetic, Plaque psoriasis, is highly prevalent form of psoriasis and basically an autoimmune disease which is challenging to treat. Being the skin disorder plaque is visible mostly on the skin, which causes red and white plaque of dead skin cel.READ MORE

Author: Habibur RAloe Vera High Molecular Polysaccharidesan
health benefits associated with Aloe vera have been attributed to the polysaccharide contained in the gel of the leaves. On the other hand, the important pharmaceutical applications such as the use of the dried Aloe vera gel powder as an excipient in sustained release (SR) pharmaceutical dosage forms, development of wa.READ MORE

Author Anurapa C, Suseem S.R*
oral control delivery system of highly water-soluble drug using aloe vera powder as a carrier for matrix tablet. Ascorbic acid is taken as a model drug for its high solubility. Different concentrations such as 30 %, 40 % and 50 % of matrix tablets of Aloe Vera powder are made by wet granulation technique using starch p.READ MORE

Author Z Zheng, X Pan, L Luo, Q Zhang, X Huang, Y Liu
Polysaccharides have been widely used as biomaterials and drugs after oral administration due to their suitable physicochemical properties, good bioactivities and low toxicities, pharmacokinetics and absorption mechanism, oral administration, polysaccharide detection technologies such as immunoassays, fluorescent and i.READ MORE

Author Z Zheng, X Pan, L Luo, Q Zhang, X Huang, Y Liu
Polysaccharides have been widely used as biomaterials and drugs after oral administration due to their suitable physicochemical properties, good bioactivities and low toxicities, pharmacokinetics and absorption mechanism, oral administration, polysaccharide detection technologies such as immunoassays, fluorescent and i.READ MORE

Author Imran KT, Gore S, Giradkar P.
treatment of illness has been accomplished by administrating drugs to human body via various routes namely oral, sublingual, rectal, parental, topical, inhalation etc. Topical delivery can be defined as the application of a drug containing formulation to the skin to directly treat cutaneous disorders like acne or the c.READ MORE

Author Erica Españo,Jiyeon Kim and Jeong-Ki Kim
Aloe barbadensis, Aloe vera, antivirals, adjuvants, immunomodulator, phytochemicals, aloe emodin, aloin, acemannan, natural products, viral outbreaks, Plants, primary sources of new bioactive compounds, novel bioactive compounds, acetylated mannans, immunomodulatory effects, antiviral activities, Aloe Compounds for the.READ MORE

Author: Suwimon Jettanacheawchankit 1, Siriruk Sasithanasate, Polkit Sangvanich, Wijit Banlunara, Pasutha Thunyakitpisal
wound healing, Gingival fibroblasts (GFs) play an important role in oral wound healing, acemannan, a polysaccharide extracted from Aloe vera gel, keratinocyte growth factor-1 (KGF-1), vascular endothelial growth factor (VEGF), and type I collagen production, cell proliferation, type I collagen expressions, extracellula.READ MORE

Author Tafara Jambwa, Alvaro Viljoen, Josias Hamman
pharmaceutical industry endeavours to develop novel drug delivery systems which require excipients that full specific functions. Excipients from renewable sources are attractive due to their sustainable mass production. The purpose of this study is to investigate the potential use of gel and whole leaf materials from A.READ MORE

Author: Tafara Jambwa, Alvaro Viljoen, Josias Hamman
pharmaceutical industry endeavours to develop novel drug delivery systems which require excipients that full specific functions. Excipients from renewable sources are attractive due to their sustainable mass production. The purpose of this study is to investigate the potential use of gel and whole leaf materials from A.READ MORE

Author: Tafara Jambwa, Alvaro Viljoen, Josias Hamman
pharmaceutical industry endeavours to develop novel drug delivery systems which require excipients that full specific functions. Excipients from renewable sources are attractive due to their sustainable mass production. The purpose of this study is to investigate the potential use of gel and whole leaf materials from A.READ MORE

Author: DEVARAJ SRIDEVI ET AL
Vitamin/supplement intake is associated with decreased mortality, Aloe vera, a botanical is consumed by 50% of the US population and may affect bioavailability of vitamin, Aloe improved vitamin C absorption. Since oral B12 is deficient in vegetarians and in aging, bioavailability of vitamins, C and B12, in older health.READ MORE

Author: Antoni Femenia, Emma S.Sánchez, Susana Simal Carmen Rosselló
acetylated mannose-rich polymer that functions as storage polysaccharide, and a galacturonic acid-rich polymer as the main component comprising the cell walls of the parenchymatous tissue, .READ MORE

Authors Kiran Sharma, Ashu Mittal, Nitesh Chauhan
Skin penetration enhancers, enhancing drug penetration into the skin through transdermal drug delivery system or topical administration, skin penetration enhancers are molecules which reversibly remove the barrier resistance of the stratum corneum and allow drugs to penetrate more readily to the .READ MORE

bioactives are dominated by acemannan, a type of carbohydrate, and related complexes of saccharides, proteins, and lipids, management of cutaneous and some systemic conditions, such as some forms of immune dysfunction, atherogenesis, malignancy, and numerous cell functions, bioactive glycan components, diverse function.READ MORE

Author Charoen Choonhakarn, Ploysyne Busaracome, Bungorn Sripanidkulchai, Pongdech Sarakarn
efficacy of Aloe Vera and 0.1% triamcinolone acetonide (TA) in mild to moderate plaque psoriasis, clinical response were evaluated using the Psoriasis Area Severity Index (PASI) and the Dermatology Life Quality Index (DLQI), AV cream may be more effective than 0.1% % triamcinolone acetonide cream in reducing the clinic.READ MORE

Author Panahi Y, Sharif MR, Sharif A, Beiraghdar F, Zahiri Z, Amirchoopani G, et al.
Diaper dermatitis (DD) is a common inflammatory disorder among children and infants, It refers to any acute inflammatory skin eruption that occurs in area covered by diaper and caused by either direct effect of wearing diapers or as a result of increased skin pH, zinc deficiency, prolonged exposure to moisture, and irr.READ MORE

Author Bathini Chandrahas, A. Jayakumar, A. Naveen, K. Butchibabu, P. K. Reddy, T. Muralikrishna
efficacy of Aloe Vera mouth rinse on experimental plaque accumulation and gingivitis, Plaque control and prevention of gingivitis is the main goal of prevention of periodontal diseases.Complete plaque removal is difficult to achieve, and prevention of periodontal disease can be enhanced either by reducing the quantity .READ MORE

Author: Prashant Singh*, Tarique Mahmood, Arshiya Shameem, Paramdeep Bagga, Nesar Ahmad
Herbal or natural excipients have a great advantage over their synthetic analogues, herbal excipients, which are manly polymers of natural origin, the pharmaceutical industries are getting more inclined towards their use in formulation development, natural excipients which can be proposed to be used as diluent, binder,.READ MORE

Author Sneha Bahuguna, Deepika Joshi*, Bhavana Singh and Nidhi Semwal
Delivery of herbal drugs as novel formulations faces hurdles due to difficulties in identification, processing, standardizing, extracting of herbal drugs with an intention to accomplish sustained and controlled release. Now with the innovation in the technologies, nano formulations paves pathway for the development of .READ MORE

Author: Choi S, Chung MH.
Aloe barbadensis Miller, immunomodulatory, antiinflammatory, UV protective, antiprotozoal, and wound- and burn-healing promoting properties, relationships between the components of aloe vera and their pharmacologic effects, promote wound, burn, and frost-bite healing, in addition to having antiinflammatory, antifungal,.READ MORE

Author: Barbara Joanna Bałan , Marcin Niemcewicz, Janusz Kocik , Leszek Jung , Ewa Skopińska-Różewska , Piotr Skopiński
aloe gel; antibody production; chemokinesis; mice; proliferation; splenocytes, antimicrobial activity, dietary supplement, Immunomodulation, chronic infections, polysaccharides (pectins, hemicelluloses, glucomannan, acemannan, and other mannose derivatives), stimulatory effect, Aloe vera extract, an increase in CD4 lym.READ MORE

Author Nicholas J Sadgrove 1, Monique S J Simmonds
Scientific studies of Aloe vera, therapeutic claims, breakage of acemannan chains into smaller fragments enhances biological effects, immune system to attack cancer cells by mannose receptor agonism of macrophage or dendritic cells, aloe vera oral consumption, small intestine or colon, dietary acemannan, acemannan is d.READ MORE

Author: Ningyang Lia1 Chaofan Wanga1 Milen I.Georgievbc Vivek K. Bajpaid Rosa Tundise Jesus Simal-Gandaraf Xiaoming LuaJianbo XiaofXiaozhen Tanga Xuguang Qiao
dietary polysaccharides as anticancer agents, nutritious dietary supplements, side effect-free therapeutics, biomacromolecules, Natural anticancer polysaccharides, physicochemical properties.READ MORE

Author Jettanacheawchankit, S.; Sasithanasate, S.; Sangvanich, P.; Banlunara, W.; Thunyakitpisal, P..
Gingival fibroblasts, GF proliferation; keratinocyte growth factor-1, vascular endothelial growth factor (VEGF),and type I collagen production, acemannan, Aloe vera, proliferation, growth factor, oral wound healing, immunostimulant effect by activating macrophages.READ MORE

Author: Gerardo Daniel Sierra-Garcíaa , Rocío Castro-Ríosc , Azucena González-Hortaa , Jorge Lara-Ariasb and Abelardo Chávez-Montes
Acemannan medicinal, properties like osteogenic, anti-inflammatory, and antibacterial, accelerate healing of lesions, antiviral , antitumor activities in vivo through activation of immune responses, immune-stimulating [9], anti-neoplasic [10] and wound-healing actions, Biochemistry of acemannan, A.READ MORE